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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $29 | In Stock | |
1 mL x 10 mM (in DMSO) | $45 | In Stock |
Description | Ipidacrine (NIK‐247) (NIK‐247) is an Antidementia Agent |
In vivo | A single oral administration of ipidacrine (0.3 and 1 mg/kg) reduced the increased total latency induced by scopolamine in this task.?The repeated administration of ipidacrine (1 mg/kg) of once a day for 5 successive days reduced the increased total latency induced by scopolamine to the levels of the saline-treated control rats in this task.Ipidacrine was rapidly taken up into the brain within 5 min. Moreover, higher drug levels were observed mainly in the cortex and hippocampus, which both play important roles in learning and memory.?Thus, a previous study together with this investigation indicate that ipidacrine improves amnesia which consists of the impairment of the working and reference memory in various animal models, suggesting that ipidacrine is a useful candidate for the therapy of patients with Alzheimer's disease[1]. |
Alias | NIK‐247 |
Molecular Weight | 188.27 |
Formula | C12H16N2 |
Cas No. | 62732-44-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 10 mg/mL (53.11 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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