Shopping Cart
- Remove All
Your shopping cart is currently empty
JC-10
Catalog No. TD0056Cas No. 5563-28-0
JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.
JC-10
Catalog No. TD0056Cas No. 5563-28-0
JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $569 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "JC-10"
Doxycycline
Cited
Vibramycin, Doxytetracycline, Doxycyclinum, Doxiciclina
T1687564-25-0
Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity.
- $45
Size
QTY
CitedDoxycycline (hyclate)
WC2031, Doxycycline hydrochloride hemiethanolate hemihydrate, Doxycycline hyclate
T1687L24390-14-5
Doxycycline hyclate (WC2031) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline hyclate has antibacterial activity and antitumor activity.
- $41
Size
QTY
Glucosamine Cited
D-Glucosamine, Chitosamine
T04293416-24-8
Glucosamine (Chitosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Supplemental glucosamine may help to rebuild cartilage and treat arthritis.
- $50
Size
QTY
CitedAstragaloside IV Cited
AST-IV, AS-IV
T297384687-43-4
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.
- $32
Size
QTY
CitedStigmasterol Cited
Stigmasterin, beta-Stigmasterol
T296783-48-7
Stigmasterol (Stigmasterin) is a phytosterol with major functions in the maintenance of cell membrane structure and physiology. Stigmasterol lowers cholesterol levels and has anti-tumor, anti-inflammatory, and immunomodulatory effects.
- $55
Size
QTY
CitedEdaravone Cited
MCI-186
T040789-25-8
Edaravone (MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.
- $43
Size
QTY
CitedGlucosamine sulfate
D-Glucosaminesulfate, D-Glucosamine sulphate
T279229031-19-4
Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.
- $41
Size
QTY
Triolein
Glycerol trioleate, Glycerine Trioleate
T3S0640122-32-7
Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.
- $39
Size
QTY
Chondroitin sulfate Cited
Chonsurid, Chondroitin polysulfate
T29809007-28-7
Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition
- $47
Size
QTY
CitedEthyl gallate Cited
Phyllemblin, Nipagallin A, gallic acid ethyl ester
T3729831-61-8
Ethyl gallate (gallic acid ethyl ester) obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhibit the abilities of invasion of breast cancer in vitro by inhibiting the mRNA levels of MMP-9/MMP-2, phosphorylation of Akt and protein expression of NF-κB and inhibits hydrogen peroxide signaling, may represent an alternative class of vasopressors for use in septic shock. Also, Ethyl gallate suppresses proliferation and invasion in human breast cancer cells by modulating the PI3K/Akt pathway, which may contribute to inhibiting their downstream targets such as NF-κB p-65, Bcl-2/Bax, and mRNA levels of MMP-2 and MMP-9 in breast cancer cells, could be used as potential antioxidants with safe therapeutic application in cancer chemotherapy.
- $42
Size
QTY
CitedSelect Batch
Purity:95%
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe. |
| Molecular Weight | 583.34 |
| Formula | C25H29Cl2IN4 |
| Cas No. | 5563-28-0 |
Storage & Solubility Information
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy JC-10 | purchase JC-10 | JC-10 cost | order JC-10 | JC-10 chemical structure | JC-10 formula | JC-10 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.