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KM04416

🥰Excellent
Catalog No. T73442Cas No. 26530-26-7
Alias KM 04416

KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.

KM04416

KM04416

🥰Excellent
Purity: 99.88%
Catalog No. T73442Alias KM 04416Cas No. 26530-26-7
KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.
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2 mg$67In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.
In vitro
KM04416 (20 µM, 48 h) was able to show growth inhibition on a variety of cancer cell lines.
KM04416 (10 µM, 72 h) significantly reduced the proliferation of PNT1A cells.[1]
AliasKM 04416
Chemical Properties
Molecular Weight249.29
FormulaC12H11NO3S
Cas No.26530-26-7
SmilesO=C(OCC)C1=CC=C(C=C1)N2SC=CC2=O
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 40 mg/mL (160.46 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0114 mL20.0570 mL40.1139 mL200.5696 mL
5 mM0.8023 mL4.0114 mL8.0228 mL40.1139 mL
10 mM0.4011 mL2.0057 mL4.0114 mL20.0570 mL
20 mM0.2006 mL1.0028 mL2.0057 mL10.0285 mL
50 mM0.0802 mL0.4011 mL0.8023 mL4.0114 mL
100 mM0.0401 mL0.2006 mL0.4011 mL2.0057 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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