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LUF6096
🥰Excellent
Catalog No. T9180Cas No. 1116652-18-6
Alias CF-602
LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors. It displays protective effects in myocardial ischemia/reperfusion injury.
LUF6096
🥰Excellent
Purity: 100%
Catalog No. T9180Alias CF-602Cas No. 1116652-18-6
LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors. It displays protective effects in myocardial ischemia/reperfusion injury.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 46 € | In Stock | |
| 2 mg | 69 € | In Stock | |
| 5 mg | 112 € | In Stock | |
| 10 mg | 186 € | In Stock | |
| 25 mg | 317 € | In Stock | |
| 50 mg | 448 € | In Stock | |
| 100 mg | 638 € | In Stock | |
| 500 mg | Inquiry | In Stock | |
| 1 mL x 10 mM (in DMSO) | 128 € | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors. It displays protective effects in myocardial ischemia/reperfusion injury. |
| In vitro | LUF6096 (10 μM; 30-120 min) reduces the dissociation rate of 125I-AB-MECA from the A3 receptor by 2.5 times in CHO cell membranes and, when pretreated for 15 min, significantly enhances the intrinsic activity of Cl-IB-MECA in inhibiting forskolin-stimulated cAMP production in CHO cells[1]. |
| In vivo | LUF6096 (twice i.v. bolus at 0.5 mg/kg or single i.v. bolus at 1 mg/kg) protects against myocardial ischemia/reperfusion injury in dogs[1]. |
| Alias | CF-602 |
| Molecular Weight | 414.33 |
| Formula | C22H21Cl2N3O |
| Cas No. | 1116652-18-6 |
| Smiles | Clc1ccc(Nc2cc(NC(=O)C3CCCCC3)c3ccccc3n2)cc1Cl |
| Relative Density. | 1.370 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (96.54 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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