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Magnesium isoglycyrrhizinate hydrate

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Catalog No. TN7831Cas No. 658701-67-8
Alias Tianqingganmei, 18α-Glycyrrhizic acid Magnesium hydrate

Magnesium isoglycyrrhizinate hydrate (18α-Glycyrrhizic acid Magnesium hydrate) is an active ingredient derived from licorice with anti-inflammatory properties. It lowers alanine and aspartate aminotransferase activities and can be used in HIV-1 infection research.

Magnesium isoglycyrrhizinate hydrate

Magnesium isoglycyrrhizinate hydrate

🥰Excellent
Catalog No. TN7831Alias Tianqingganmei, 18α-Glycyrrhizic acid Magnesium hydrateCas No. 658701-67-8
Magnesium isoglycyrrhizinate hydrate (18α-Glycyrrhizic acid Magnesium hydrate) is an active ingredient derived from licorice with anti-inflammatory properties. It lowers alanine and aspartate aminotransferase activities and can be used in HIV-1 infection research.
Pack SizePriceAvailabilityQuantity
1 mg28 € In Stock
5 mg62 € In Stock
10 mg93 € In Stock
25 mg158 € In Stock
50 mg236 € In Stock
100 mg354 € In Stock
200 mg532 € In Stock
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Product Introduction

Bioactivity
Description
Magnesium isoglycyrrhizinate hydrate (18α-Glycyrrhizic acid Magnesium hydrate) is an active ingredient derived from licorice with anti-inflammatory properties. It lowers alanine and aspartate aminotransferase activities and can be used in HIV-1 infection research.
In vivo
Magnesium isoglycyrrhizinate hydrate (15 or 45 mg/kg.d, i.p., 18 days) was effective in inhibiting ethanol-induced spermatogenic epithelial tissue division and degeneration of supporting cells and germ cells, and was protective against oxidative damage of testis. [1]
Magnesium isoglycyrrhizinate hydrate (0.40 or 0.80 mg/kg/d) exerts anti-inflammatory activity through the NLRP3 inflammatome pathway and improves chronic obstructive pulmonary disease in rats ina rat model. [2]
AliasTianqingganmei, 18α-Glycyrrhizic acid Magnesium hydrate
Chemical Properties
Molecular Weight917.28
FormulaC42H68MgO20
Cas No.658701-67-8
SmilesC[C@]12[C@@](C(C=C3[C@]2(CC[C@@]4([C@]3([H])C[C@](C)(CC4)C(O)=O)C)C)=O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C([O-])=O)O)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C([O-])=O)C)([H])CC1)C.[Mg+2].O.O.O.O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 20 mg/mL (21.8 mM), when pH is adjusted to 9 with NH3·H2O.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.0902 mL5.4509 mL10.9018 mL54.5090 mL
5 mM0.2180 mL1.0902 mL2.1804 mL10.9018 mL
10 mM0.1090 mL0.5451 mL1.0902 mL5.4509 mL
20 mM0.0545 mL0.2725 mL0.5451 mL2.7254 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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