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Methyl 3-(2,4-dihydroxyphenyl)propionate
🥰Excellent
Catalog No. TN4527Cas No. 17422-90-1
Methyl 3-(2,4-dihydroxyphenyl)propionate is a novel vitamin E derivative that inhibits tyrosinase, which is an antioxidant and inhibits UV-B-induced hyperpigmentation, with potential whitening effects.
Methyl 3-(2,4-dihydroxyphenyl)propionate
🥰Excellent
Purity: 98.62%
Catalog No. TN4527Cas No. 17422-90-1
Methyl 3-(2,4-dihydroxyphenyl)propionate is a novel vitamin E derivative that inhibits tyrosinase, which is an antioxidant and inhibits UV-B-induced hyperpigmentation, with potential whitening effects.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $31 | In Stock | |
| 200 mg | $44 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $39 | In Stock |
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View MoreInhibitors Related to "Methyl 3-(2,4-dihydroxyphenyl)propionate"
Hexylresorcinol
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CitedGlycolic acid
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Glycolic acid, an inhibitor of tyrosinase, suppresses melanin formation and is used in skincare products.
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Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties. Benzylacetone has a strong and reversible anti-mushroom tyrosinase effect, with IC50 values of 2.8 mM and 0.6 mM for monophenolase and biphenolase effects, respectively.
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Aloin
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Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
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Potassium iodide Cited
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- $31
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Purity:98.62%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Methyl 3-(2,4-dihydroxyphenyl)propionate is a novel vitamin E derivative that inhibits tyrosinase, which is an antioxidant and inhibits UV-B-induced hyperpigmentation, with potential whitening effects. |
| In vitro | Methods: A novel vitamin E derivative, (6"-hydroxy-2",5",7",8"-tetramethylchroman-2"-yl)methyl 3-(2,4-dihydroxyphenyl)propionate (TM4R), which has a chromanoxy ring and a 4-substituted resorcinol moiety, was synthesized and evaluated for its inhibitory activity against tyrosinase, antioxidant capacity, and lightening effect on ultraviolet B (UVB)-induced hyperpigmentation. Results: Methyl 3-(2,4-dihydroxyphenyl)propionate exhibited potent inhibitory activity against tyrosinase, the rate-limiting enzyme in melanogenesis. The scavenging activity of methyl 3-(2,4-dihydroxyphenyl)propionate against 1,1-diphenyl-2-picrylhydrazyl and hydroxyl radicals was found to be almost the same as that of α-tocopherol. Furthermore, an effective whitening effect was observed after topical application of methyl 3-(2,4-dihydroxyphenyl)propionate on UVB-stimulated pigmented dorsal skin of brown guinea pigs. Conclusion: These Results suggest that methyl 3-(2,4-dihydroxyphenyl)propionate may be an effective skin-whitening agent, possibly by inhibiting tyrosinase activity and biological responses induced by reactive oxygen species.[1] |
| Molecular Weight | 196.2 |
| Formula | C10H12O4 |
| Cas No. | 17422-90-1 |
| Smiles | O=C(OC)CCC1=CC=C(O)C=C1O |
| Relative Density. | 1.260 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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