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Methyl Cholate

Name: Methyl Cholate
Brand: TargetMol
SKU: T2744
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Methyl Cholate is the methyl ester form of cholic acid. Methyl Cholate is the methyl ester form of bile acid, which is a major bile acid produced by the liver and synthesized from cholesterol.Methyl Cholate has anti-inflammatory and anti-tumor activity.

Catalog No. T2744Cas No. 1448-36-8

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Purity:99.83%

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COA HPLC HNMR

Methyl Cholate

Catalog No. T2744Cas No. 1448-36-8

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Pack Size	Price	Availability
200 mg	$35	In Stock
500 mg	$55	In Stock
1 g	$78	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Related Compound Libraries of "Methyl Cholate"

Product Introduction

Bioactivity

Description	Methyl Cholate is the methyl ester form of cholic acid. Methyl Cholate is the methyl ester form of bile acid, which is a major bile acid produced by the liver and synthesized from cholesterol.Methyl Cholate has anti-inflammatory and anti-tumor activity.
Kinase Assay	Collagenase assay uses the synthetic thiol ester substrate Ac-Pro-Leu-Gly-SCH(i-Bu)CO-Leu-Gly-OEt at pH 6.5. The collagenase concentration is 1-2 nM, and the substrate concentrations are from 0.1 to 0.7 nM. Km?is found to vary between 1.5 and 4 mM.
Alias	Cholic acid methyl ester

Chemical Properties

Molecular Weight	422.6
Formula	C₂₅H₄₂O₅
Cas No.	1448-36-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (130.14 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3663 mL	11.8315 mL	23.6630 mL	118.3152 mL
5 mM	0.4733 mL	2.3663 mL	4.7326 mL	23.6630 mL
10 mM	0.2366 mL	1.1832 mL	2.3663 mL	11.8315 mL
20 mM	0.1183 mL	0.5916 mL	1.1832 mL	5.9158 mL
50 mM	0.0473 mL	0.2366 mL	0.4733 mL	2.3663 mL
100 mM	0.0237 mL	0.1183 mL	0.2366 mL	1.1832 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

inhibitCholic acidMethylInhibitorMethyl Cholatecholesterol