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Mps1-IN-3
Catalog No. T16130Cas No. 1609584-72-6
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
Mps1-IN-3
Catalog No. T16130Cas No. 1609584-72-6
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $41 | In Stock | |
| 2 mg | $59 | In Stock | |
| 5 mg | $97 | In Stock | |
| 10 mg | $155 | In Stock | |
| 25 mg | $296 | In Stock | |
| 50 mg | $547 | In Stock | |
| 100 mg | $789 | In Stock | |
| 1 mL x 5 mM (in DMSO) | $115 | In Stock |
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Purity:99.25%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM). |
| Targets&IC50 | Mps1:50 nM |
| In vitro | Mps1-IN-3 inhibits the proliferation of U251 glioblastoma cells (IC50: appr 5 μM). Mps1-IN-3 is an effective inhibitor of MPS1 kinase (IC50: 50 nM). Mps1-IN-3 (2 μM) can completely abrogates checkpoint. |
| In vivo | Mps1-IN-3 (2 mg/kg, i.v.) enhances the sensitivity of glioblastoma cells in murine tumor models, extends survival, and exhibits no toxicity. |
| Molecular Weight | 537.63 |
| Formula | C26H31N7O4S |
| Cas No. | 1609584-72-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (111.6 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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