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Netarsudil mesylate
Catalog No. T10358L2Cas No. 1422144-42-0
Alias AR-13324 mesylate, AR13324 mesylate
Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.
Netarsudil mesylate
Catalog No. T10358L2Alias AR-13324 mesylate, AR13324 mesylateCas No. 1422144-42-0
Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $328 | In Stock | |
| 50 mg | $528 | In Stock | |
| 100 mg | $936 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension. |
| In vivo | 0.04% Netarsudil mesylate reduces intraocular pressure (IOP) in normotensive monkey eyes . [1] 0.04% Netarsudil mesylate produces a statistically significant lowering of episcleral venous pressure (EVP) in Dutch Belted rabbits . [2] |
| Alias | AR-13324 mesylate, AR13324 mesylate |
| Molecular Weight | 645.74 |
| Formula | C30H35N3O9S2 |
| Cas No. | 1422144-42-0 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL(123.89 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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