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Neticonazole
🥰Excellent
Catalog No. T35335Cas No. 130726-68-0
Alias SS-717, SS717, SS 717
Neticonazole (SS717) is an imidazole derivative with antifungal activity that inhibits exosome secretion. Neticonazole has anti-infective and anti-cancer effects, can induce contact dermatitis, and can be used to study skin Candida albicans infections.
Neticonazole
🥰Excellent
Purity: 99.58%
Catalog No. T35335Alias SS-717, SS717, SS 717Cas No. 130726-68-0
Neticonazole (SS717) is an imidazole derivative with antifungal activity that inhibits exosome secretion. Neticonazole has anti-infective and anti-cancer effects, can induce contact dermatitis, and can be used to study skin Candida albicans infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $33 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $73 | In Stock |
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Purity:99.58%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Neticonazole (SS717) is an imidazole derivative with antifungal activity that inhibits exosome secretion. Neticonazole has anti-infective and anti-cancer effects, can induce contact dermatitis, and can be used to study skin Candida albicans infections. |
| Targets&IC50 | Exosome: |
| In vitro | Neticonazole against 39 T. rubrum isolates (MIC80, 0.125 μg/ml) and 28 T. mentagrophytes isolates (MIC80, 0.25 μg/ml). Neticonazole against 39 T. rubrum isolates (MFC80, 0.25 μg/ml) and 28 T. mentagrophytes isolates (MFC 80, 0.25 μg/ml). [1] |
| In vivo | A clinical isolate of C. albicans, isolate KC-36, was used for production of experimental cutaneous candidiasis in guinea pigs. The MICs of Neticonazole for the test strain were 0.0625. [1] |
| Alias | SS-717, SS717, SS 717 |
| Molecular Weight | 302.43 |
| Formula | C17H22N2OS |
| Cas No. | 130726-68-0 |
| Smiles | C(=C\SC)(\C1=C(OCCCCC)C=CC=C1)/N2C=CN=C2 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | 1M HCl: 80 mg/mL（264.52 mM), when pH is adjusted to 1 with 1M HCl.Sonication is recommended. DMSO: 200 mg/mL（661.31 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
1M HCl/DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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