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Nicotelline

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Catalog No. T78135Cas No. 494-04-2
Alias Nicotellin

Nicotelline, also known as Nicotellin, is an alkaloid associated with nicotine and acts as a modest inhibitor of the enzyme human cDNA-expressed cytochrome P-450 2A6 (CYP2A6), which is responsible for coumarin 7-hydroxylation. However, Nicotelline does not show inhibitory effects at a concentration of 300 μM. It serves as a tracer and biomarker for particulate matter (PM) originating from tobacco smoke [1] [2].

Nicotelline

Nicotelline

😃Good
Catalog No. T78135Alias NicotellinCas No. 494-04-2
Nicotelline, also known as Nicotellin, is an alkaloid associated with nicotine and acts as a modest inhibitor of the enzyme human cDNA-expressed cytochrome P-450 2A6 (CYP2A6), which is responsible for coumarin 7-hydroxylation. However, Nicotelline does not show inhibitory effects at a concentration of 300 μM. It serves as a tracer and biomarker for particulate matter (PM) originating from tobacco smoke [1] [2].
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2 mg$415 days
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Product Introduction

Bioactivity
Description
Nicotelline, also known as Nicotellin, is an alkaloid associated with nicotine and acts as a modest inhibitor of the enzyme human cDNA-expressed cytochrome P-450 2A6 (CYP2A6), which is responsible for coumarin 7-hydroxylation. However, Nicotelline does not show inhibitory effects at a concentration of 300 μM. It serves as a tracer and biomarker for particulate matter (PM) originating from tobacco smoke [1] [2].
Targets&IC50
CYP26:≥300 μM (Ki)
AliasNicotellin
Chemical Properties
Molecular Weight233.27
FormulaC15H11N3
Cas No.494-04-2
Storage & Solubility Information
StorageShipping with blue ice.

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