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Nicotelline

🥰Excellent
Catalog No. T78135Cas No. 494-04-2
Alias Nicotellin

Nicotelline (Nicotellin) is a biomarker and environmental tracer for tobacco smoke particles, a relatively non-volatile alkaloid found in tobacco smoke, and a weak inhibitor of cytochrome P-450 2A6 (CYP2A6). It is used to distinguish tobacco products.

Nicotelline

Nicotelline

🥰Excellent
Purity: 99.92%
Catalog No. T78135Alias NicotellinCas No. 494-04-2
Nicotelline (Nicotellin) is a biomarker and environmental tracer for tobacco smoke particles, a relatively non-volatile alkaloid found in tobacco smoke, and a weak inhibitor of cytochrome P-450 2A6 (CYP2A6). It is used to distinguish tobacco products.
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2 mg$41In Stock
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Purity:99.92%
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Product Introduction

Bioactivity
Description
Nicotelline (Nicotellin) is a biomarker and environmental tracer for tobacco smoke particles, a relatively non-volatile alkaloid found in tobacco smoke, and a weak inhibitor of cytochrome P-450 2A6 (CYP2A6). It is used to distinguish tobacco products.
Targets&IC50
CYP26:≥300 μM (Ki)
In vitro
Nicotelline can be used as a tracer and biomarker for PM. [1]
AliasNicotellin
Chemical Properties
Molecular Weight233.27
FormulaC15H11N3
Cas No.494-04-2
SmilesN1=CC=CC(=C1)C=2N=CC=C(C2)C=3C=NC=CC3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (342.95 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.2869 mL21.4344 mL42.8688 mL214.3439 mL
5 mM0.8574 mL4.2869 mL8.5738 mL42.8688 mL
10 mM0.4287 mL2.1434 mL4.2869 mL21.4344 mL
20 mM0.2143 mL1.0717 mL2.1434 mL10.7172 mL
50 mM0.0857 mL0.4287 mL0.8574 mL4.2869 mL
100 mM0.0429 mL0.2143 mL0.4287 mL2.1434 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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