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Methotrexate Diglutamate

Catalog No. T25886Cas No. 41600-13-9
Alias NSC-269401, NSC269401, NSC 269401

Methotrexate Diglutamate Small molecule compound present in the liver that acts as a partially purified human dihydrofolate reductase inhibitor.

Methotrexate Diglutamate

Methotrexate Diglutamate

Purity: 98.84%
Catalog No. T25886Alias NSC-269401, NSC269401, NSC 269401Cas No. 41600-13-9
Methotrexate Diglutamate Small molecule compound present in the liver that acts as a partially purified human dihydrofolate reductase inhibitor.
Pack SizePriceAvailabilityQuantity
1 mg$1,630In Stock
5 mg$3,280In Stock
10 mg$4,430In Stock
25 mg$6,580In Stock
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Related Compound Libraries of "Methotrexate Diglutamate"

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Purity:98.84%
ee:97.90%
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Product Introduction

Bioactivity
Description
Methotrexate Diglutamate Small molecule compound present in the liver that acts as a partially purified human dihydrofolate reductase inhibitor.
AliasNSC-269401, NSC269401, NSC 269401
Chemical Properties
Molecular Weight583.55
FormulaC25H29N9O8
Cas No.41600-13-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (171.3 mM), Sonification is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7136 mL8.5682 mL17.1365 mL85.6825 mL
5 mM0.3427 mL1.7136 mL3.4273 mL17.1365 mL
10 mM0.1714 mL0.8568 mL1.7136 mL8.5682 mL
20 mM0.0857 mL0.4284 mL0.8568 mL4.2841 mL
50 mM0.0343 mL0.1714 mL0.3427 mL1.7136 mL
100 mM0.0171 mL0.0857 mL0.1714 mL0.8568 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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