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Opc 8490
🥰Excellent
Catalog No. T33807Cas No. 123941-50-4
Alias Opc-8490, Opc8490
Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator that increases Ca current (ICa) in a dose-dependent and reversible manner and prolongs atrial action potential in a concentration-dependent manner.
Opc 8490
🥰Excellent
Purity: 98.69%
Catalog No. T33807Alias Opc-8490, Opc8490Cas No. 123941-50-4
Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator that increases Ca current (ICa) in a dose-dependent and reversible manner and prolongs atrial action potential in a concentration-dependent manner.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 208 € | In Stock | |
| 5 mg | 520 € | In Stock | |
| 10 mg | 752 € | In Stock | |
| 25 mg | 1.159 € | In Stock | |
| 50 mg | 1.881 € | In Stock |
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Purity:98.69%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator that increases Ca current (ICa) in a dose-dependent and reversible manner and prolongs atrial action potential in a concentration-dependent manner. |
| In vivo | Opc 8490 (0.1, 0.3, and 1 μM/kg) induced a dose-dependent decrease in heart rate and arterial blood pressure in intact assisted dogs when administered intravenously; Opc 8490 (1 μM) induced a triphasic effect, Ph1 followed by Ph2 and a slightly positive (Ph3) chronotropic and inotropic effect.[3] |
| Alias | Opc-8490, Opc8490 |
| Molecular Weight | 597.61 |
| Formula | C30H35N3O10 |
| Cas No. | 123941-50-4 |
| Smiles | O=C(O)CC(O)(C(=O)O)CC(=O)O.O=C(C1=CC=C2NC(=O)CCC2=C1)N3CCN(CC3)CCCC(=O)C=4C=CC=CC4 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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