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Pascolizumab
Catalog No. T77426Cas No. 331243-22-2
Alias SB-240683
Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis.
Pascolizumab
Pascolizumab
Catalog No. T77426Alias SB-240683Cas No. 331243-22-2
Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $228 | In Stock | |
| 5 mg | $589 | In Stock | |
| 10 mg | $959 | In Stock | |
| 25 mg | $1,420 | In Stock | |
| 50 mg | $1,920 | In Stock | |
| 100 mg | $2,590 | In Stock |
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Concentration:3.1 mg/mL
Purity:> 95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis. |
| Targets&IC50 | T cells:157pM, Tonsillar B cells:377 pM |
| In vitro | Pascolizumab binds to IL-4 and inhibits the interaction between IL-4 and its receptor alpha chain[1]. Pascolizumab (0-10000 pM; 3 days) demonstrates anti-proliferative activity with IC50 values of 157 pM for T cells and 377 pM for tonsillar B cells[1]. |
| Alias | SB-240683 |
| Molecular Weight | 147.18 kDa |
| Cas No. | 331243-22-2 |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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