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Patchouli alcohol (Patchoulol) is a naturally occurring tricyclic sesquiterpenoid found in patchouli oil. It is a key bioactive component known for its immunomodulatory, anti-inflammatory, antioxidant, antitumor, antibacterial, anti-atherosclerotic, antiemetic, and sedative properties.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $50 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Patchouli alcohol (Patchoulol) is a naturally occurring tricyclic sesquiterpenoid found in patchouli oil. It is a key bioactive component known for its immunomodulatory, anti-inflammatory, antioxidant, antitumor, antibacterial, anti-atherosclerotic, antiemetic, and sedative properties. |
In vitro | METHODS: H. pylori-infected GES-1 cells were treated with Patchouli alcohol (5-20 µg/mL) for 24 h. Apoptosis was detected by flow cytometry. RESULTS: Patchouli alcohol treatment significantly reduced H. pylori-induced apoptosis. [1] METHODS: H. pylori-infected GES-1 cells were treated with Patchouli alcohol (5-20 µg/mL) for 24 h, and cytokine levels were measured by ELISA. RESULTS: 5-20 µg/mL Patchouli alcohol treatment significantly reduced the production of TNF-α and MCP-1. [1] |
In vivo | METHODS: To study the effect on H. pylori-associated gastritis, Patchouli alcohol (5-20 mg/kg) was administered orally to H. pylori-infected mice once daily for two weeks. RESULTS: Patchouli alcohol treatment increased SH-NP content and CAT activity, and significantly protected the gastric mucosa from H. pylori-induced damage. [1] |
Alias | Patchoulol, Patchouli camphor, (-)-Patchouli Alcohol |
Molecular Weight | 222.37 |
Formula | C15H26O |
Cas No. | 5986-55-0 |
Smiles | [H][C@@]12CC[C@@]3(C)[C@]([H])(C1)[C@@H](C)CC[C@@]3(O)C2(C)C |
Relative Density. | 1.001 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (202.37 mM) Ethanol: 15 mg/mL | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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