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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $40 | In Stock | |
10 mg | $64 | In Stock | |
25 mg | $106 | In Stock | |
50 mg | $155 | In Stock |
Description | Pheophorbide A is a photosensitizer used in in vivo photodynamic therapy (PDT).Phoophorbide A is a lymphatic vasoreactivator with antioxidant, anti-inflammatory, antitumor, and hypoglycemic activities.Phoophorbide A is used in research on diabetes and cancer. |
In vitro | Pheophorbide A significantly inhibited the growth of Hep3B cells with an IC50 value of 1.5 μM. The intracellular ROS level was increased in the cells treated with Pa-PDT, and the cytotoxic effect could be reversed when ascorbic acid was applied[2]. |
In vivo | In male immunocompetent C3H mice ( six-week-old, inoculated subcutaneously with AT-84 cells ), Pheophorbide A ( 10 mg / kg intravenous ( i.v. ) or a 30 mg / kg intraperitoneal ( i.p. ) injection ; after 24 h) significantly inhibited tumor growth up to 70 %[1]。 |
Molecular Weight | 592.68 |
Formula | C35H36N4O5 |
Cas No. | 15664-29-6 |
Storage | keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 1 mg/mL (1.69 mM) DMF: 1 mg/mL (1.69 mM) DMSO:PBS(pH 7.2) (1:3): 0.25 mg/mL Methanol: < 1 mg/mL (Insoluble) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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