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Pomalidomide-PEG3-CO2H

Pomalidomide-PEG3-CO2H
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Purity:99.05%
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Pomalidomide-PEG3-CO2H

Catalog No. T40023Cas No. 2138440-82-9
Pomalidomide-PEG3-CO2H (Thalidomide-NH-PEG3-propionic acid) is a synthesized E3 ligase ligand-linker conjugate. Pomalidomide-PEG3-CO2H incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
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Pack SizePriceAvailabilityQuantity
5 mg$36In Stock
10 mg$52In Stock
25 mg$88In Stock
50 mgInquiryIn Stock
100 mgInquiryIn Stock
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Product Introduction

Bioactivity
Description
Pomalidomide-PEG3-CO2H (Thalidomide-NH-PEG3-propionic acid) is a synthesized E3 ligase ligand-linker conjugate. Pomalidomide-PEG3-CO2H incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
AliasThalidomide-NH-PEG3-propionic acid
Chemical Properties
Molecular Weight477.46
FormulaC22H27N3O9
Cas No.2138440-82-9
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 100 mg/mL (209.4 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0944 mL10.4721 mL20.9442 mL104.7208 mL
5 mM0.4189 mL2.0944 mL4.1888 mL20.9442 mL
10 mM0.2094 mL1.0472 mL2.0944 mL10.4721 mL
20 mM0.1047 mL0.5236 mL1.0472 mL5.2360 mL
50 mM0.0419 mL0.2094 mL0.4189 mL2.0944 mL
100 mM0.0209 mL0.1047 mL0.2094 mL1.0472 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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