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(S,R,S)-AHPC-PEG3-NH2 hydrochloride

🥰Excellent
Catalog No. T17922Cas No. 2097971-11-2
Alias VHL Ligand-Linker Conjugates 1 hydrochloride, VHL Ligand-Linker Conjugates 1 HCl, VH032-PEG3-NH2 hydrochloride, E3 ligase Ligand-Linker Conjugates 5

(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate that integrates the (S,R,S)-AHPC-based VHL ligand with a 3-unit PEG linker.

(S,R,S)-AHPC-PEG3-NH2 hydrochloride

(S,R,S)-AHPC-PEG3-NH2 hydrochloride

🥰Excellent
Purity: 97.58%
Catalog No. T17922Alias VHL Ligand-Linker Conjugates 1 hydrochloride, VHL Ligand-Linker Conjugates 1 HCl, VH032-PEG3-NH2 hydrochloride, E3 ligase Ligand-Linker Conjugates 5Cas No. 2097971-11-2
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate that integrates the (S,R,S)-AHPC-based VHL ligand with a 3-unit PEG linker.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$64In Stock
25 mg$128In Stock
50 mg$238In Stock
100 mg$452In Stock
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Purity:97.58%
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Product Introduction

Bioactivity
Description
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate that integrates the (S,R,S)-AHPC-based VHL ligand with a 3-unit PEG linker.
AliasVHL Ligand-Linker Conjugates 1 hydrochloride, VHL Ligand-Linker Conjugates 1 HCl, VH032-PEG3-NH2 hydrochloride, E3 ligase Ligand-Linker Conjugates 5
Chemical Properties
Molecular Weight656.23
FormulaC30H46ClN5O7S
Cas No.2097971-11-2
SmilesC([C@@H](NC(COCCOCCOCCN)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1.Cl
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (68.6 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5239 mL7.6193 mL15.2386 mL76.1928 mL
5 mM0.3048 mL1.5239 mL3.0477 mL15.2386 mL
10 mM0.1524 mL0.7619 mL1.5239 mL7.6193 mL
20 mM0.0762 mL0.3810 mL0.7619 mL3.8096 mL
50 mM0.0305 mL0.1524 mL0.3048 mL1.5239 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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