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Thalidomide-O-amido-C4-NH2 TFA

🥰Excellent
Catalog No. T7759Cas No. 1799711-25-3
Alias E3 ligase Ligand-Linker Conjugates 19 TFA, Cereblon Ligand-Linker Conjugates 6 TFA

Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized compound that functions as an E3 ligase ligand-linker conjugate.

Thalidomide-O-amido-C4-NH2 TFA

Thalidomide-O-amido-C4-NH2 TFA

🥰Excellent
Purity: 95%
Catalog No. T7759Alias E3 ligase Ligand-Linker Conjugates 19 TFA, Cereblon Ligand-Linker Conjugates 6 TFACas No. 1799711-25-3
Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized compound that functions as an E3 ligase ligand-linker conjugate.
Pack SizePriceAvailabilityQuantity
5 mg$32In Stock
10 mg$47In Stock
25 mg$77In Stock
50 mg$116In Stock
1 mL x 10 mM (in DMSO)$44In Stock
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Purity:95%
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Product Introduction

Bioactivity
Description
Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized compound that functions as an E3 ligase ligand-linker conjugate.
AliasE3 ligase Ligand-Linker Conjugates 19 TFA, Cereblon Ligand-Linker Conjugates 6 TFA
Chemical Properties
Molecular Weight516.42
FormulaC21H23F3N4O8
Cas No.1799711-25-3
SmilesO=C(NCCCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(O)C(F)(F)F
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 40 mg/mL (77.46 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9364 mL9.6820 mL19.3641 mL96.8204 mL
5 mM0.3873 mL1.9364 mL3.8728 mL19.3641 mL
10 mM0.1936 mL0.9682 mL1.9364 mL9.6820 mL
20 mM0.0968 mL0.4841 mL0.9682 mL4.8410 mL
50 mM0.0387 mL0.1936 mL0.3873 mL1.9364 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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