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Thalidomide-NH-C4-NH-Boc

🥰Excellent
Catalog No. T18807Cas No. 2093388-52-2

Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.

Thalidomide-NH-C4-NH-Boc

Thalidomide-NH-C4-NH-Boc

🥰Excellent
Purity: 98.87%
Catalog No. T18807Cas No. 2093388-52-2
Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$68In Stock
10 mg$113In Stock
25 mg$228In Stock
50 mg$378In Stock
100 mg$612In Stock
500 mg$1,280In Stock
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Purity:98.87%
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Product Introduction

Bioactivity
Description
Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.
Chemical Properties
Molecular Weight444.48
FormulaC22H28N4O6
Cas No.2093388-52-2
SmilesO=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCNC(OC(C)(C)C)=O
Relative Density.1.324 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (112.49 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2498 mL11.2491 mL22.4982 mL112.4910 mL
5 mM0.4500 mL2.2498 mL4.4996 mL22.4982 mL
10 mM0.2250 mL1.1249 mL2.2498 mL11.2491 mL
20 mM0.1125 mL0.5625 mL1.1249 mL5.6246 mL
50 mM0.0450 mL0.2250 mL0.4500 mL2.2498 mL
100 mM0.0225 mL0.1125 mL0.2250 mL1.1249 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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