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PPTN
🥰Excellent
Catalog No. T12530Cas No. 1160271-30-6
PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity.
PPTN
🥰Excellent
Purity: 100%
Catalog No. T12530Cas No. 1160271-30-6
PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 111 € | In Stock | |
| 5 mg | 255 € | In Stock | |
| 10 mg | 375 € | In Stock | |
| 25 mg | 562 € | In Stock | |
| 50 mg | 792 € | In Stock | |
| 100 mg | 1.064 € | In Stock | |
| 500 mg | 2.147 € | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity. |
| Targets&IC50 | P2Y14 receptor:434 pM (KB) |
| In vitro | PPTN exhibits strong selectivity for the P2Y14-R over the other seven nucleotide-activated P2Y receptors. It inhibits UDP-glucose-promoted chemotaxis in differentiated HL-60 human promyelocytic leukemia cells, with IC50s of approximately 1 nM in the presence of 10 μM UDP-glucose and around 4 nM in the presence of 100 μM[1]. |
| Molecular Weight | 475.5 |
| Formula | C29H24F3NO2 |
| Cas No. | 1160271-30-6 |
| Smiles | C(O)(=O)C=1C=C(C2=C(C=C(C=C2)C3=CC=C(C(F)(F)F)C=C3)C1)C4=CC=C(C=C4)C5CCNCC5 |
| Relative Density. | 1.259 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMSO: 1.58 mg/ml (3.33 mM), Sonication is recommended.  Ethanol: insoluble | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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