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Roburic acid

🥰Excellent
Catalog No. T3883Cas No. 6812-81-3

Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.

Roburic acid

Roburic acid

🥰Excellent
Purity: 99.88%
Catalog No. T3883Cas No. 6812-81-3
Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$97In Stock
10 mg$189In Stock
25 mg$328In Stock
50 mg$493In Stock
100 mg$689In Stock
1 mL x 10 mM (in DMSO)$129In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.
Targets&IC50
COX-1:5 μM (IC50), COX-2:9 μM (IC50)
Chemical Properties
Molecular Weight440.7
FormulaC30H48O2
Cas No.6812-81-3
SmilesC[C@@H]1CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@](C)(CCC(O)=O)[C@@H](CC[C@@]34C)C(C)=C)[C@@H]2[C@H]1C
Relative Density.1.02 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (136.14 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2691 mL11.3456 mL22.6912 mL113.4559 mL
5 mM0.4538 mL2.2691 mL4.5382 mL22.6912 mL
10 mM0.2269 mL1.1346 mL2.2691 mL11.3456 mL
20 mM0.1135 mL0.5673 mL1.1346 mL5.6728 mL
50 mM0.0454 mL0.2269 mL0.4538 mL2.2691 mL
100 mM0.0227 mL0.1135 mL0.2269 mL1.1346 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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