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(S,S)-Secoisolariciresinol diglucoside

🥰Excellent
Catalog No. TN5418Cas No. 257930-74-8
Alias Secoisolariciresinol diglucoside, (S,S)-SDG

(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.

(S,S)-Secoisolariciresinol diglucoside

(S,S)-Secoisolariciresinol diglucoside

🥰Excellent
Purity: 99.33%
Catalog No. TN5418Alias Secoisolariciresinol diglucoside, (S,S)-SDGCas No. 257930-74-8
(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.
Pack SizePriceAvailabilityQuantity
2 mg$51In Stock
5 mg$81In Stock
10 mg$140In Stock
25 mg$269In Stock
50 mg$383In Stock
100 mg$655In Stock
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Purity:99.33%
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Product Introduction

Bioactivity
Description
(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.
In vitro
Secoisolariciresinol diglucoside is a major lignan component in flaxseed and exhibits potent antioxidant activity in vitro, acting as an effective scavenger of free hydroxyl radicals[1].
In vivo
Secoisolariciresinol diglucoside (oral administration; 4 mg/mouse) administered to 10-week-old male mice 2 hours before the administration of tumor necrosis factor alpha (TNFα) significantly reduced the adhesion of leukocytes to the endothelium by 50% and the migration of leukocytes across the blood-brain barrier by 64%[2].
AliasSecoisolariciresinol diglucoside, (S,S)-SDG
Chemical Properties
Molecular Weight686.7
FormulaC32H46O16
Cas No.257930-74-8
Smiles[C@@H]([C@H](CC1=CC(OC)=C(O)C=C1)CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(CC3=CC(OC)=C(O)C=C3)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.1.52 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 80 mg/mL (116.50 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.4562 mL7.2812 mL14.5624 mL72.8120 mL
5 mM0.2912 mL1.4562 mL2.9125 mL14.5624 mL
10 mM0.1456 mL0.7281 mL1.4562 mL7.2812 mL
20 mM0.0728 mL0.3641 mL0.7281 mL3.6406 mL
50 mM0.0291 mL0.1456 mL0.2912 mL1.4562 mL
100 mM0.0146 mL0.0728 mL0.1456 mL0.7281 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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