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SET 2
🥰Excellent
Catalog No. T37097Cas No. 2313525-20-9
SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.
SET 2
🥰Excellent
Purity: 98.43%
Catalog No. T37097Cas No. 2313525-20-9
SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $53 | In Stock | |
| 10 mg | $88 | In Stock | |
| 25 mg | $187 | In Stock | |
| 50 mg | $316 | In Stock | |
| 100 mg | $461 | In Stock | |
| 500 mg | Inquiry | In Stock | |
| 1 mL x 10 mM (in DMSO) | $65 | In Stock |
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Purity:98.43%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4. |
| Targets&IC50 | TRPV2:0.46 μM |
| In vitro | In PC-3M cells, SET 2 (20 μM) suppresses cell migration without inhibiting cell viability and inhibits 2-APB-evoked current transiently co-transfected with TRPV2 and LPAR1[1]. |
| Molecular Weight | 402.43 |
| Formula | C17H21F3N4O2S |
| Cas No. | 2313525-20-9 |
| Smiles | CCCN(C)c1cc(nc(SCCC(=O)NCc2ccco2)n1)C(F)(F)F |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (124.25 mM), Sonication is recommended.  Ethanol: 20.12 mg/mL (50 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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