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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $2,390 | 7-10 days |
Description | SGD-1882 is a cytotoxic, DNA minor-groove crosslinking pyrrolobenzodiazepine (PBD) dimer, serving as the payload for ADCs [antibody-drug conjugates]. |
In vitro | SGD-1882 is not an MDR1 substrate, and SGN-CD33A is conjugated to the SGD-1882. SGN-CD33A can kill MDR1 expressing CD33 positive AML patient samples and is currently in Phase I[2]. |
Alias | PBD dimer |
Molecular Weight | 725.79 |
Formula | C42H39N5O7 |
Cas No. | 1222490-34-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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