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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $39 | In Stock | |
100 mg | $57 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Sodium gualenate (Guaiazulenesulfonate sodium) (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects. |
In vivo | Sodium gualenate is frequently used to treat human gastritis, with its primary mechanism of action being the cytoprotection of the stomach's mucosal lining [1]. |
Animal Research | The anti-gastric ulcer activity of compounds was tested through an ethanol-induced gastric ulcer mouse model method.?Kunming mice, consisting of both males and females, each weighing about 25 g, were divided into groups of 8 at random.?The tested compounds, Omeprazole and guaiazulene derivatives which were made into suspensions using 5% CMC-Na were administered orally (0.4 mL/20 g) to the dose group, the drug reference group and the GAS-Na group respectively.?While the base control group was treated with only 5% CMC-Na.?Vehicle or test compounds were administered by the oral route once a day for five consecutive days.?After 0.5 h of the last dose, the mice were given orally 0.3 mL of anhydrous ethanol.?Half an hour after anhydrous ethanol administration, the animals were killed.?At last, the stomachs were removed and scored[1]. |
Alias | Guaiazulenesulfonate sodium |
Molecular Weight | 300.35 |
Formula | C15H17NaO3S |
Cas No. | 6223-35-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 30 mg/mL (99.88 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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