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TBT1

🥰Excellent
Catalog No. T61042Cas No. 52535-76-9

TBT1 is a novel MsbA transporter protein inhibitor and MsbA ATPase stimulator, which inhibits the synthesis of ATP-dependent transporter proteins in the lipopolysaccharide synthesis pathway.TBT1 possesses antimicrobial activity, which inhibits Salmonella, Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus, and it can be used in the study of bacterial infections.

TBT1

TBT1

🥰Excellent
Purity: 99.27%
Catalog No. T61042Cas No. 52535-76-9
TBT1 is a novel MsbA transporter protein inhibitor and MsbA ATPase stimulator, which inhibits the synthesis of ATP-dependent transporter proteins in the lipopolysaccharide synthesis pathway.TBT1 possesses antimicrobial activity, which inhibits Salmonella, Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus, and it can be used in the study of bacterial infections.
Pack SizePriceAvailabilityQuantity
1 mg$93In Stock
5 mg$228In Stock
10 mg$372In Stock
25 mg$689In Stock
50 mg$1,090In Stock
100 mg$1,780In Stock
200 mg$2,380In Stock
1 mL x 10 mM (in DMSO)$253In Stock
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Purity:99.27%
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Product Introduction

Bioactivity
Description
TBT1 is a novel MsbA transporter protein inhibitor and MsbA ATPase stimulator, which inhibits the synthesis of ATP-dependent transporter proteins in the lipopolysaccharide synthesis pathway.TBT1 possesses antimicrobial activity, which inhibits Salmonella, Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus, and it can be used in the study of bacterial infections.
Chemical Properties
Molecular Weight335.81
FormulaC16H14ClNO3S
Cas No.52535-76-9
SmilesOC(=O)c1c(NC(=O)c2ccc(Cl)cc2)sc2CCCCc12
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (297.79 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9779 mL14.8894 mL29.7787 mL148.8937 mL
5 mM0.5956 mL2.9779 mL5.9557 mL29.7787 mL
10 mM0.2978 mL1.4889 mL2.9779 mL14.8894 mL
20 mM0.1489 mL0.7445 mL1.4889 mL7.4447 mL
50 mM0.0596 mL0.2978 mL0.5956 mL2.9779 mL
100 mM0.0298 mL0.1489 mL0.2978 mL1.4889 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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