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TH1085

Name: TH1085
Brand: TargetMol
SKU: T60034
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60034Cas No. 1002801-51-5

TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).

TH1085

🥰Excellent

Purity: 99.92%

Catalog No. T60034Cas No. 1002801-51-5

TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).

Pack Size	Price	Availability
1 mg	$44	In Stock
2 mg	$62	In Stock
5 mg	$98	In Stock
10 mg	$163	In Stock
25 mg	$313	In Stock
50 mg	$497	In Stock
100 mg	$723	In Stock
500 mg	$1,520	In Stock
1 mL x 10 mM (in DMSO)	$116	In Stock

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L400017520 compounds

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L401026102 compounds

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Purity:99.92%

Resource Download

COA HPLC HNMR

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Product Introduction

Bioactivity

Description

TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).

Chemical Properties

Molecular Weight	267.37
Formula	C₁₇H₂₁N₃
Cas No.	1002801-51-5
Smiles	C1CC1c1nc(NC2CCCCC2)c2ccccc2n1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (187.01 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7401 mL	18.7007 mL	37.4014 mL	187.0068 mL
5 mM	0.7480 mL	3.7401 mL	7.4803 mL	37.4014 mL
10 mM	0.3740 mL	1.8701 mL	3.7401 mL	18.7007 mL
20 mM	0.1870 mL	0.9350 mL	1.8701 mL	9.3503 mL
50 mM	0.0748 mL	0.3740 mL	0.7480 mL	3.7401 mL
100 mM	0.0374 mL	0.1870 mL	0.3740 mL	1.8701 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TH-1085TH1085TH-10785TH10785TH 1085TH 10785phenylalanineInhibitorinhibitglycineenzymeDNA oxidative lesionsDNA glycosylase 1 (OGG1)8-oxoguanine DNA glycosylase 1 (OGG1)