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TLR1
Catalog No. T13932Cas No. 566914-00-9
TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $122 | In Stock | |
| 5 mg | $297 | In Stock | |
| 10 mg | $453 | In Stock | |
| 25 mg | $733 | In Stock | |
| 50 mg | $987 | In Stock | |
| 100 mg | $1,360 | In Stock | |
| 500 mg | $2,720 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $313 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses. |
| In vitro | In EL4 thymoma cells and in freshly isolated murine lymphocytes, TLR1 inhibits IL-1β-induced phosphorylation of the mitogen-activated protein kinase p38 in a concentration-dependent manner. |
| In vivo | TLR1 produces a significant attenuation of the IL-1β-induced fever response (200 mg/kg, i.p.). |
| Molecular Weight | 302.41 |
| Formula | C18H26N2O2 |
| Cas No. | 566914-00-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (99.2 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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