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Vatinoxan hydrochloride
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Catalog No. T13285Cas No. 130466-38-5
Alias MK-467 hydrochloride, L-659066 hydrochloride
Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.
Vatinoxan hydrochloride
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Catalog No. T13285Alias MK-467 hydrochloride, L-659066 hydrochlorideCas No. 130466-38-5
Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $2,120 | 8-10 weeks | |
| 50 mg | $2,780 | 8-10 weeks | |
| 100 mg | $3,700 | 8-10 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors. |
| In vivo | When given simultaneously i.v Vatinoxan alone increases cardiac index and tissue oxygen delivery and has no deleterious adverse effects.In a dose-dependent manner Vatinoxan attenuates or prevents dexmedetomidine's systemic hemodynamic effects. A 50:1 dose ratio (Vatinoxan:dexmedetomidine) induces the least alterations in cardiovascular function[1]. Vatinoxan dose-dependently reduces bradycardia associated with dexmedetomidine and shortens the sedative effect without changing its quality. Vatinoxan may help reduce heart rate reduction in cats consciously administering dexmedetomidine[2]. |
| Alias | MK-467 hydrochloride, L-659066 hydrochloride |
| Molecular Weight | 454.97 |
| Formula | C20H27ClN4O4S |
| Cas No. | 130466-38-5 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 133 mg/mL (292.33 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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