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VTP-27999 TFA

🥰Excellent
Catalog No. T7668Cas No. 1013937-63-7

VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).

VTP-27999 TFA

VTP-27999 TFA

🥰Excellent
Purity: 99.72%
Catalog No. T7668Cas No. 1013937-63-7
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
Pack SizePriceAvailabilityQuantity
1 mg$34In Stock
5 mg$81In Stock
10 mg$137In Stock
25 mg$289In Stock
50 mg$483In Stock
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Purity:99.72%
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Product Introduction

Bioactivity
Description
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
Targets&IC50
Renin:0.47 nM
In vitro
In vitro,VTP-27999 increased renin immunoreactivity for a given amount of renin by ≥ 30%[]1
Chemical Properties
Molecular Weight639.1
FormulaC28H42ClF3N4O7
Cas No.1013937-63-7
SmilesOC(=O)C(F)(F)F.CN[C@H](CNC(=O)N1CCC[C@H](C1)[C@@H](OCCNC(=O)OC)c1cccc(Cl)c1)C[C@H]1CCCOC1
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 10 mg/mL (15.65 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.5647 mL7.8235 mL15.6470 mL78.2350 mL
5 mM0.3129 mL1.5647 mL3.1294 mL15.6470 mL
10 mM0.1565 mL0.7824 mL1.5647 mL7.8235 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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