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Zymosan A
🥰Excellent
Catalog No. T78101Cas No. 58856-93-2
Alias Zymosan A from Saccharomyces cerevisia
Zymosan A, a polysaccharide from Saccharomyces cerevisiae (brewer's yeast), is a TLR2 agonist that promotes regeneration of ISCs from intestinal stem cells after radiation injury by up-regulating ASCL2 through the TLR2 signaling pathway and the Wnt signaling pathway.Zymosan A stimulates immune responses and induces inflammation , anorexia and elevated body temperature, and also inhibits the gap junction protein connexin 43 in human corneal fibroblasts and causes corneal stromal damage.
Zymosan A
Zymosan A
🥰Excellent
Catalog No. T78101Alias Zymosan A from Saccharomyces cerevisiaCas No. 58856-93-2
Zymosan A, a polysaccharide from Saccharomyces cerevisiae (brewer's yeast), is a TLR2 agonist that promotes regeneration of ISCs from intestinal stem cells after radiation injury by up-regulating ASCL2 through the TLR2 signaling pathway and the Wnt signaling pathway.Zymosan A stimulates immune responses and induces inflammation , anorexia and elevated body temperature, and also inhibits the gap junction protein connexin 43 in human corneal fibroblasts and causes corneal stromal damage.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $35 | In Stock | |
| 100 mg | $52 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Zymosan A, a polysaccharide from Saccharomyces cerevisiae (brewer's yeast), is a TLR2 agonist that promotes regeneration of ISCs from intestinal stem cells after radiation injury by up-regulating ASCL2 through the TLR2 signaling pathway and the Wnt signaling pathway.Zymosan A stimulates immune responses and induces inflammation , anorexia and elevated body temperature, and also inhibits the gap junction protein connexin 43 in human corneal fibroblasts and causes corneal stromal damage. |
| In vivo | Methods: Zymosan A (25.0 mg/Kg, intraperitoneal injection, 24 and 2 hours before IR) was given to mice to observe its effect on IR-induced intestinal damage in mice. Results: The radioprotective effect of Zymosan A was even better when it was given 24 and 2 hours before IR. Zymosan A had a significant radioprotective effect on irradiated mice, and Zymosan A alleviated IR-induced intestinal damage in mice. [1] |
| Alias | Zymosan A from Saccharomyces cerevisia |
| Cas No. | 58856-93-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O: < 1 mg/mL (insoluble) DMSO: 1 mg/mL, adjust pH to 4 with HCl |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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