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α,β-Methylene ATP trisodium

Name: α,β-Methylene ATP trisodium
Brand: TargetMol
SKU: T13541
Rating: 4.5 (1 reviews)

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Catalog No. T13541Cas No. 1343364-54-4

α,β-Methylene ATP trisodium, a phosphonate analog of ATP, is a selective P2X agonist that induces enhanced contraction of UBSM. α,β-Methylene ATP trisodium inhibits P2X1 and P2X3, but is inactive against P2X2, 4 and 7.

α,β-Methylene ATP trisodium

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Purity: 99.66%

Catalog No. T13541Cas No. 1343364-54-4

Pack Size	Price	Availability
25 mg	$1,650	8-10 weeks
50 mg	$2,150	8-10 weeks
100 mg	$3,480	8-10 weeks

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Purity:99.66%

Resource Download

COA PNMR HNMR HPLC

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	571.15
Formula	C₁₁H₁₅N₅Na₃O₁₂P₃
Cas No.	1343364-54-4
Smiles	O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(CP(OP([O-])(O)=O)([O-])=O)([O-])=O)N2C3=NC=NC(N)=C3N=C2.[Na+].[Na+].[Na+]
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 100 mg/mL (175.09 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.7509 mL	8.7543 mL	17.5085 mL	87.5427 mL
5 mM	0.3502 mL	1.7509 mL	3.5017 mL	17.5085 mL
10 mM	0.1751 mL	0.8754 mL	1.7509 mL	8.7543 mL
20 mM	0.0875 mL	0.4377 mL	0.8754 mL	4.3771 mL
50 mM	0.0350 mL	0.1751 mL	0.3502 mL	1.7509 mL
100 mM	0.0175 mL	0.0875 mL	0.1751 mL	0.8754 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc