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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $268 | Backorder | |
200 mg | $418 | Backorder | |
500 mg | $995 | Backorder |
Description | (S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | VH032-PEG2-NH2, VHL Ligand-Linker Conjugates 3, E3 ligase Ligand-Linker Conjugates 6 Free Base |
Molecular Weight | 575.72 |
Formula | C28H41N5O6S |
Cas No. | 2010159-60-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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