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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $97 | In Stock | |
250 mg | $197 | In Stock |
Description | DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery. |
In vitro | Each siRNA is encapsulated in LNP (cationic lipid-A: PEG2000-DMPE: DOPE = 47.8: 5.18: 47.1 molar percent). With the neutral lipid for the LNP is DOPE, LNP exerts knock-down (KD) effect on macrophages and DCs and Liposome-containing DOPE shows fusogenicity. LNP/siRNA significantly suppresses CD45 protein expression at an inhibition rate of 30% on macrophages and DCs but not on monocytes, neutrophils, plasmacytoid DCs, or B cells. |
Molecular Weight | 744.03 |
Formula | C41H78NO8P |
Cas No. | 4004-05-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: <1 mg/mL(insoluble or slightly soluble) ![]() |
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