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12-Ethyl-9-hydroxycamptothecin

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Catalog No. TN2460Cas No. 119577-28-5
Alias 7-Ethyl-10-Hydroxy-Camptothecin

12-Ethyl-9-hydroxycamptothecin (SN38) is the active metabolite of irinotecan, a topoisomerase I inhibitor, with potential anticancer activity for use in the study of colon and rectal cancer.

12-Ethyl-9-hydroxycamptothecin

12-Ethyl-9-hydroxycamptothecin

🥰Excellent
Catalog No. TN2460Alias 7-Ethyl-10-Hydroxy-CamptothecinCas No. 119577-28-5
12-Ethyl-9-hydroxycamptothecin (SN38) is the active metabolite of irinotecan, a topoisomerase I inhibitor, with potential anticancer activity for use in the study of colon and rectal cancer.
Pack SizePriceAvailabilityQuantity
5 mg$41In Stock
10 mg$58In Stock
25 mg$94In Stock
50 mg$137In Stock
100 mg$197In Stock
200 mg$293In Stock
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Product Introduction

Bioactivity
Description
12-Ethyl-9-hydroxycamptothecin (SN38) is the active metabolite of irinotecan, a topoisomerase I inhibitor, with potential anticancer activity for use in the study of colon and rectal cancer.
Alias7-Ethyl-10-Hydroxy-Camptothecin
Chemical Properties
Molecular Weight392.41
FormulaC22H20N2O5
Cas No.119577-28-5
SmilesO=C1N2C(C=3C(C2)=CC=4C(N3)=C(CC)C=CC4O)=CC5=C1COC(=O)[C@@]5(CC)O
Relative Density.1.51 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (203.87 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5484 mL12.7418 mL25.4836 mL127.4178 mL
5 mM0.5097 mL2.5484 mL5.0967 mL25.4836 mL
10 mM0.2548 mL1.2742 mL2.5484 mL12.7418 mL
20 mM0.1274 mL0.6371 mL1.2742 mL6.3709 mL
50 mM0.0510 mL0.2548 mL0.5097 mL2.5484 mL
100 mM0.0255 mL0.1274 mL0.2548 mL1.2742 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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