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12-Ketodeoxycholic acid

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Catalog No. T14002Cas No. 5130-29-0

12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].

12-Ketodeoxycholic acid

12-Ketodeoxycholic acid

🥰Excellent
Purity: 99.25%
Catalog No. T14002Cas No. 5130-29-0
12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].
Pack SizePriceAvailabilityQuantity
5 mg$57In Stock
10 mg$81In Stock
25 mg$131In Stock
50 mg$196In Stock
100 mg$287In Stock
1 mL x 10 mM (in DMSO)$77In Stock
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Purity:99.25%
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Product Introduction

Bioactivity
Description
12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].
In vitro
Bile acids, resulting from the conjugation of cholesterol, are synthesized by the liver and subsequently secreted into the intestine[1] for incorporation into bile.
Chemical Properties
Molecular Weight390.56
FormulaC24H38O4
Cas No.5130-29-0
SmilesC[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@H](O)CC[C@]4(C)[C@H]3CC(=O)[C@]12C
Relative Density.1.124 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (256.04 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5604 mL12.8021 mL25.6043 mL128.0213 mL
5 mM0.5121 mL2.5604 mL5.1209 mL25.6043 mL
10 mM0.2560 mL1.2802 mL2.5604 mL12.8021 mL
20 mM0.1280 mL0.6401 mL1.2802 mL6.4011 mL
50 mM0.0512 mL0.2560 mL0.5121 mL2.5604 mL
100 mM0.0256 mL0.1280 mL0.2560 mL1.2802 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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