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15(S)-HpETE
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Catalog No. T35943Cas No. 70981-96-3
Alias 15S-HpETE
15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis. 15(S)-HpETE can upregulate the expression of CD31, E-selectin, and gene selectin in cells.
15(S)-HpETE
😃Good
Catalog No. T35943Alias 15S-HpETECas No. 70981-96-3
15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis. 15(S)-HpETE can upregulate the expression of CD31, E-selectin, and gene selectin in cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $93 | 35 days | |
| 50 μg | $163 | 35 days | |
| 100 μg | $296 | 35 days | |
| 250 μg | $693 | 35 days |
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Concentration:0.1 mg/mL
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Product Introduction
Bioactivity
Chemical Properties
| Description | 15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis. 15(S)-HpETE can upregulate the expression of CD31, E-selectin, and gene selectin in cells. |
| In vitro | 15(S)-HpETE is involved in the regulation of a variety of cell signaling pathways and biological processes by inducing the expression of c-fos and c-jun genes and activating AP-1 transcription factor. This regulatory mechanism is important for understanding inflammatory responses, cellular stress responses, and other diseases related to lipid metabolism. [1] |
| Alias | 15S-HpETE |
| Molecular Weight | 336.47 |
| Formula | C20H32O4 |
| Cas No. | 70981-96-3 |
| Smiles | [C@@H](/C=C/C=C\C/C=C\C/C=C\CCCC(O)=O)(CCCCC)OO |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | 0.1 M Na2CO3: <1 mg/mL (Insoluble or slightly soluble.) PBS (pH 7.2): <1 mg/mL (Insoluble or slightly soluble.) DMSO: Miscible DMF: Miscible Ethanol: Miscible |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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