Powder: -20°C for 3 years | In solvent: -80°C for 1 year
25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regulation of cholesterol biosynthesis after an acute dietary cholesterol challenge. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 45.00 | |
10 mg | In stock | $ 61.00 | |
25 mg | In stock | $ 93.00 | |
50 mg | In stock | $ 142.00 | |
100 mg | In stock | $ 223.00 |
Description | 25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regulation of cholesterol biosynthesis after an acute dietary cholesterol challenge. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells. |
Molecular Weight | 402.65 |
Formula | C27H46O2 |
CAS No. | 2140-46-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 20 mg/mL
Chloroform: 50 mg/mL
You can also refer to dose conversion for different animals. More
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25-Hydroxycholesterol 2140-46-7 Metabolism Others HMG-CoA Reductase Endogenous Metabolite Inhibitor inhibit 25Hydroxycholesterol 25 Hydroxycholesterol inhibitor