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3-Methyladipic acid

Catalog No. T5253   CAS 3058-01-3

3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation. This pathway produces 3-methyladipic acid as the final metabolite, which is excreted in the urine.

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3-Methyladipic acid Chemical Structure
3-Methyladipic acid, CAS 3058-01-3
Pack Size Availability Price/USD Quantity
500 mg In stock $ 41.00
1 g In stock $ 48.00
1 mL * 10 mM (in DMSO) In stock $ 45.00
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Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation. This pathway produces 3-methyladipic acid as the final metabolite, which is excreted in the urine.
Molecular Weight 160.17
Formula C7H12O4
CAS No. 3058-01-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 200 mM

TargetMolReferences and Literature

1. Wierzbicki AS, et al. Refsum's disease: a peroxisomal disorder affecting phytanic acid alpha-oxidation. J Neurochem. 2002 Mar;80(5):727-35.

Related compound libraries

This product is contained In the following compound libraries:
Human Endogenous Metabolite Library Natural Product Library for HTS Traditional Chinese Medicine Monomer Library Natural Product Library RO5 Drug-like Natural Product Library Gut Microbial Metabolite Library Human Endogenous Metabolite Compound Library Plus Human Metabolite Library

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Keywords

3-Methyladipic acid 3058-01-3 Metabolism Others Endogenous Metabolite 3Methyladipic acid inhibit Inhibitor 3 Methyladipic acid inhibitor

 

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