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Histone acetyltransferase p300 Inhibitor 4c

Histone acetyltransferase p300 Inhibitor 4c
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Purity:99.86%
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Histone acetyltransferase p300 Inhibitor 4c

Catalog No. T77560Cas No. 2103-99-3
Histone acetyltransferase p300 Inhibitor 4c is a 2-aminothiazole derivative. Histone acetyltransferase p300 Inhibitor 4c inhibited hCA I, hCA II, AChE and BChE with Ki values of 0.008 ± 0.001, 0.124 ± 0.017, 0.129 ± 0.030 and 0.083 ± 0.041 µM. 0.017, 0.129 ± 0.030 and 0.083 ± 0.041 μM.
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500 mg$31In Stock
1 g$44In Stock
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Product Introduction

Bioactivity
Description
Histone acetyltransferase p300 Inhibitor 4c is a 2-aminothiazole derivative. Histone acetyltransferase p300 Inhibitor 4c inhibited hCA I, hCA II, AChE and BChE with Ki values of 0.008 ± 0.001, 0.124 ± 0.017, 0.129 ± 0.030 and 0.083 ± 0.041 µM. 0.017, 0.129 ± 0.030 and 0.083 ± 0.041 μM.
Chemical Properties
Molecular Weight210.68
FormulaC9H7ClN2S
Cas No.2103-99-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (237.33 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.7465 mL23.7327 mL47.4654 mL237.3268 mL
5 mM0.9493 mL4.7465 mL9.4931 mL47.4654 mL
10 mM0.4747 mL2.3733 mL4.7465 mL23.7327 mL
20 mM0.2373 mL1.1866 mL2.3733 mL11.8663 mL
50 mM0.0949 mL0.4747 mL0.9493 mL4.7465 mL
100 mM0.0475 mL0.2373 mL0.4747 mL2.3733 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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