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Ulodesine

Ulodesine
Ulodesine (BCX4208) is a purine nucleoside phosphorylase (PNP) inhibitor that inhibits PNP with an IC50 value of 2.293 nM/L. Ulodesine may be used to study hyperuricaemia.
Catalog No. T67822LCas No. 548486-59-5
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Ulodesine

Catalog No. T67822LAlias BCX4208Cas No. 548486-59-5

Ulodesine (BCX4208) is a purine nucleoside phosphorylase (PNP) inhibitor that inhibits PNP with an IC50 value of 2.293 nM/L. Ulodesine may be used to study hyperuricaemia.
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Pack SizePriceAvailabilityQuantity
1 mg$139In Stock
5 mg$347In Stock
10 mg$563In Stock
25 mg$890In Stock
50 mg$1,230In Stock
100 mg$1,670In Stock
500 mg$3,350In Stock
1 mL x 10 mM (in DMSO)$317In Stock
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Product Introduction

Bioactivity
Description
Ulodesine (BCX4208) is a purine nucleoside phosphorylase (PNP) inhibitor that inhibits PNP with an IC50 value of 2.293 nM/L. Ulodesine may be used to study hyperuricaemia.
Targets&IC50
PNP:2.293 nM
In vivo
Ulodesine intravenously effectively eradicates uric acid accumulations in the bloodstream of the mouse model.[1]
AliasBCX4208
Chemical Properties
Molecular Weight264.28
FormulaC12H16N4O3
Cas No.548486-59-5
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 11 mg/mL (41.62 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7839 mL18.9193 mL37.8387 mL189.1933 mL
5 mM0.7568 mL3.7839 mL7.5677 mL37.8387 mL
10 mM0.3784 mL1.8919 mL3.7839 mL18.9193 mL
20 mM0.1892 mL0.9460 mL1.8919 mL9.4597 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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