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Ulodesine

🥰Excellent
Catalog No. T67822LCas No. 548486-59-5
Alias BCX4208

Ulodesine (BCX4208) is a purine nucleoside phosphorylase (PNP) inhibitor that inhibits PNP with an IC50 value of 2.293 nM/L. Ulodesine may be used to study hyperuricaemia.

Ulodesine

Ulodesine

🥰Excellent
Purity: 100%
Catalog No. T67822LAlias BCX4208Cas No. 548486-59-5
Ulodesine (BCX4208) is a purine nucleoside phosphorylase (PNP) inhibitor that inhibits PNP with an IC50 value of 2.293 nM/L. Ulodesine may be used to study hyperuricaemia.
Pack SizePriceAvailabilityQuantity
1 mg$139In Stock
5 mg$347In Stock
10 mg$563In Stock
25 mg$890In Stock
50 mg$1,230In Stock
100 mg$1,670In Stock
500 mg$3,350In Stock
1 mL x 10 mM (in DMSO)$317In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Ulodesine (BCX4208) is a purine nucleoside phosphorylase (PNP) inhibitor that inhibits PNP with an IC50 value of 2.293 nM/L. Ulodesine may be used to study hyperuricaemia.
Targets&IC50
PNP:2.293 nM
In vivo
Ulodesine intravenously effectively eradicates uric acid accumulations in the bloodstream of the mouse model.[1]
AliasBCX4208
Chemical Properties
Molecular Weight264.28
FormulaC12H16N4O3
Cas No.548486-59-5
SmilesOC[C@H]1CN(Cc2c[nH]c3c2[nH]cnc3=O)C[C@@H]1O
Relative Density.1.68 g/cm3 (Predicted)
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 11 mg/mL (41.62 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7839 mL18.9193 mL37.8387 mL189.1933 mL
5 mM0.7568 mL3.7839 mL7.5677 mL37.8387 mL
10 mM0.3784 mL1.8919 mL3.7839 mL18.9193 mL
20 mM0.1892 mL0.9460 mL1.8919 mL9.4597 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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