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6-Demethoxytangeretin

Catalog No. T8152   CAS 6601-66-7

6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus depressa.

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6-Demethoxytangeretin Chemical Structure
6-Demethoxytangeretin, CAS 6601-66-7
Pack Size Availability Price/USD Quantity
1 mg In stock $ 71.00
5 mg In stock $ 166.00
10 mg In stock $ 243.00
25 mg In stock $ 397.00
50 mg In stock $ 597.00
100 mg In stock $ 852.00
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Purity: 99.89%
Purity: 99.47%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus depressa.
In vitro 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via ALK and MAPK pathways [1]. 6-Demethoxytangeretin facilitates the Cre-mediated transcription associated with learning and memory in cultured hippocampal neurons [2].
Source
Molecular Weight 342.34
Formula C19H18O6
CAS No. 6601-66-7

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.42 mg/mL (10 mM)

TargetMolReferences and Literature

1. Kim YM, et al. A citrus flavonoid, 6-demethoxytangeretin, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase and mitogen-activated protein kinase pathways. Biol Pharm Bull. 2014;37(5):871-6. Epub 2014 Feb 5. 2. Kawahata I, et al. Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action. J Neural Transm (Vienna). 2013 Oct;120(10):1397-409.

Related compound libraries

This product is contained In the following compound libraries:
Tyrosine Kinase Inhibitor Library Anti-Colorectal Cancer Compound Library Neural Regeneration Compound Library Bioactive Compounds Library Max Anti-Aging Compound Library Anti-Cancer Compound Library Osteogenesis Compound Library Inhibitor Library Anti-Pancreatic Cancer Compound Library Natural Product Library for HTS

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Keywords

6-Demethoxytangeretin 6601-66-7 Angiogenesis MAPK Tyrosine Kinase/Adaptors ALK Cluster of differentiation 246 6Demethoxytangeretin Anaplastic lymphoma kinase (ALK) Anaplastic lymphoma kinase CD246 inhibit ALK tyrosine kinase receptor 6 Demethoxytangeretin Inhibitor inhibitor

 

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