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6-Phosphogluconic acid

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Catalog No. T10185Cas No. 921-62-0

6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI), with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate.

6-Phosphogluconic acid

6-Phosphogluconic acid

🥰Excellent
Catalog No. T10185Cas No. 921-62-0
6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI), with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate.
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5 mg$242In Stock
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Product Introduction

Bioactivity
Description
6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI), with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate.
Targets&IC50
Fructose 6-phosphate:42 μM(Ki), Glucose 6-phosphate:48 μM(Ki)
In vitro
6-Phosphogluconic acid, at concentrations ranging from 0.5 to 2.0 mM, fully inhibits the activity of phosphoglucose isomerase (PGI) when using glucose 6-phosphate, in concentrations of 0.05 to 0.5 mM, as the substrate [1].
Chemical Properties
Molecular Weight276.14
FormulaC6H13O10P
Cas No.921-62-0
SmilesO[C@H]([C@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)C(O)=O
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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