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7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $33 | In Stock | |
100 mg | $47 | In Stock | |
500 mg | $112 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | 7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts. |
In vitro | 7-Dehydrocholesterol, a biosynthetic precursor of cholesterol and vitamin D3, is found in high concentrations in the skin. Upon UV irradiation, it converts to pre-vitamin D3 and is also exposed to exogenous radical sources and oxygen. |
Alias | Provitamin D3, 7-DHC |
Molecular Weight | 384.64 |
Formula | C27H44O |
Cas No. | 434-16-2 |
Smiles | CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C |
Relative Density. | 1 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 11 mg/mL (28.6 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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