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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $78 | 35 days | |
5 mg | $363 | 35 days | |
10 mg | $653 | 35 days | |
25 mg | $1,420 | 35 days |
Description | 9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. It exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride inihibits Hela S-3 and 293T cells (IC50s: 1.6 μM and 1.2μM). |
In vitro | 9-Hydroxyellipticine selectively inhibits p53 protein phosphorylation in both Lewis lung carcinoma and SW480 (human colon cancer cell line), demonstrating a concentration-dependent effect ranging from 0.1 to 100 μM [4]. |
In vivo | 9-Hydroxyellipticine (5 or 10 mg/kg, ip) results in chromosome clumping and sister chromatid exchange in murine bone marrow cells [1]. |
Molecular Weight | 298.77 |
Formula | C17H15ClN2O |
Cas No. | 52238-35-4 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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