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AMPA receptor modulator-1

Catalog No. T10307 CAS 2036074-41-4

AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.

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AMPA receptor modulator-1 Chemical Structure

AMPA receptor modulator-1, CAS 2036074-41-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
5 mg	In stock	$ 448.00
10 mg	In stock	$ 658.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,380.00
100 mg	In stock	$ 1,890.00
1 mL * 10 mM (in DMSO)	In stock	$ 453.00

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Purity: 98.82%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
Targets&IC50	TARPγ 8:9.7

Molecular Weight	341.71
Formula	C16H11ClF3NO2
CAS No.	2036074-41-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.42 mg/mL (10 mM), Sonification is recommended

References and Literature

1. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826. 2. Hamideh Zarrinmayeh, et al.A novel class of positive allosteric modulators of AMPA receptors: Design, synthesis, and structure–activity relationships of 3-biphenyl-4-yl-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid, LY2059346.Bioorg Med Chem Lett . 2006 Oct 1;16(19):5203-6. doi: 10.1016/j.bmcl.2006.07.01Epub 2006 Jul 25

Related compound libraries

This product is contained In the following compound libraries：

Neuronal Signaling Compound Library Bioactive Compounds Library Max Bioactive Compound Library

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AMPA receptor modulator-5 AMPA receptor modulator-4 cis-PDA D-Cycloserine (RS)-(Tetrazol-5-yl)glycine Tat-NR2B9c NMDAR/TRPM4-IN-2 Nevadistinel

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Keywords

AMPA receptor modulator-1 2036074-41-4 Membrane transporter/Ion channel Neuroscience iGluR AMPA receptor modulator1 AMPA receptor modulator 1 inhibitor inhibit

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