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Aconine

Catalog No. T4S1881 CAS 509-20-6

Synonyms: Jesaconine

1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.

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Aconine, CAS 509-20-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 48.00
5 mg	In stock	$ 113.00
10 mg	In stock	$ 189.00
25 mg	In stock	$ 319.00
50 mg	In stock	$ 475.00
1 mL * 10 mM (in DMSO)	In stock	$ 125.00

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Purity: 99.61%

Purity: 99.43%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.
Source	Natural Products > Ranunculaceae > Aconitum

Synonyms	Jesaconine
Molecular Weight	499.59
Formula	C25H41NO9
CAS No.	509-20-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (90.07 mM)

References and Literature

1. Zeng X Z , He L G , Wang S , et al. Aconine inhibits RANKL-induced osteoclast differentiation in RAW264.7 cells by suppressing NF-κB and NFATc1 activation and DC-STAMP expression[J]. Acta Pharmacologica Sinica, 2015.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library NF-κB Signaling Compound Library Anti-Ovarian Cancer Compound Library Antioxidant Compound Library NO PAINS Compound Library Anti-Prostate Cancer Compound Library Anti-Liver Cancer Compound Library RO5 Drug-like Natural Product Library Pyroptosis Compound Library Alkaloid Natural Product Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Aconine 509-20-6 NF-Κb Others NF-κB Inhibitor Nuclear factor-κB inhibit Nuclear factor-kappaB Jesaconine inhibitor

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