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Alfuzosin
🥰Excellent
Catalog No. T22232Cas No. 81403-80-7
Alias SL 77499
Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.Alfuzosin has been used to study benign prostatic hypertrophy, lower urinary tract symptoms (LUTS), and ejaculatory dysfunction (EjD).
Alfuzosin
🥰Excellent
Purity: 99.64%
Catalog No. T22232Alias SL 77499Cas No. 81403-80-7
Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.Alfuzosin has been used to study benign prostatic hypertrophy, lower urinary tract symptoms (LUTS), and ejaculatory dysfunction (EjD).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $40 | In Stock | |
| 25 mg | $74 | In Stock | |
| 50 mg | $123 | In Stock | |
| 100 mg | $197 | In Stock | |
| 500 mg | $496 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock |
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Purity:99.64%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.Alfuzosin has been used to study benign prostatic hypertrophy, lower urinary tract symptoms (LUTS), and ejaculatory dysfunction (EjD). |
| In vitro | In male Wistar rats weighing 250-450 g, Alfuzosin (10 mg/kg; oral administration; single dose) increased prostatic concentrations to 4.1-8.6 times higher than plasma concentration[1]. |
| In vivo | In male Wistar rats weighing 250-450 g, Alfuzosin (10 mg/kg; oral administration; single dose) increases prostatic concentrations to 4.1-8.6 times higher than plasma concentration[1]. |
| Alias | SL 77499 |
| Molecular Weight | 389.45 |
| Formula | C19H27N5O4 |
| Cas No. | 81403-80-7 |
| Smiles | COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C1CCCO1 |
| Relative Density. | 1.272 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (102.71 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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