Aloesin

Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin.

Catalog No. T5755Cas No. 30861-27-9

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Purity:99.58%

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COA HNMR HPLC

Aloesin

Catalog No. T5755Cas No. 30861-27-9

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Pack Size	Price	Availability	Quantity
20 mg	$80	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Product Introduction

Bioactivity

Description	Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin.
In vivo	Aloesin prevents not only UV-B-induced immune suppression, but also could be a positive pigment-altering agent for cosmetic application. In preclinical study, aloe extract was investigated using phagocytosis and nitroblue tetrazolium chloride (NBT) reduction in adult bronchial asthma.

Chemical Properties

Molecular Weight	394.37
Formula	C₁₉H₂₂O₉
Cas No.	30861-27-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 78 mg/mL (197.78 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5357 mL	12.6784 mL	25.3569 mL	126.7845 mL
5 mM	0.5071 mL	2.5357 mL	5.0714 mL	25.3569 mL
10 mM	0.2536 mL	1.2678 mL	2.5357 mL	12.6784 mL
20 mM	0.1268 mL	0.6339 mL	1.2678 mL	6.3392 mL
50 mM	0.0507 mL	0.2536 mL	0.5071 mL	2.5357 mL
100 mM	0.0254 mL	0.1268 mL	0.2536 mL	1.2678 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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